12-Month Change in Bone Mineral Density

3-Month vs 12-Month EVENITY Regimens

3 Months EVENITY + 9 Months Prolia
12 Months EVENITY
Site
% Change from Baseline
3-mo
12-mo
Total HipPrimary
5.7%
6.0%
Femoral Neck
5.0%
6.3%
Lumbar Spine
10.6%
12.5%
0% 5% 10% 12.5%

Data from Leder et al., Lancet Diabetes Endocrinol 2026. No statistically significant differences between groups at any site.